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1

National Product Design Identities

Kelly Dawson, Povl Larsen, Gavin Cawood, Alan Lewis

Journal:

Creativity and Innovation Management

Year:

2005

Language:

english

File:

PDF, 102 KB

english, 2005

2

How Award-Winning SMEs Manage the Barriers to Innovation

Povl Larsen, Alan Lewis

Journal:

Creativity and Innovation Management

Year:

2007

Language:

english

File:

PDF, 84 KB

english, 2007

3

Partial GABAA Receptor Agonists. Synthesis and in Vitro Pharmacology of a Series of Nonannulated Analogs of 4,5,6,7-Tetrahydroisoxazolo[4,5-c]pyridin-3-ol

Frolund, Bente, Kristiansen, Uffe, Brehm, Lotte, Hansen, Annette B., Krogsgaard-Larsen, Povl, Falch, Erik

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.37 MB

english, 1995

4

Contribution of academic research to discovery and development of medicines: current status and future opportunities

Patrick Couvreur, Diane Braguer, Daan J.A. Crommelin, Dominique Duchêne, Joachim W. Engels, David J. Kerr, Povl Krogsgaard-Larsen, Dirk K. Meijer, Rodolfo Paoletti, Ernst Wagner

Journal:

European Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 180 KB

english, 2005

5

Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D

Hans Bräuner-Osborne, Anders A Jensen, Paul O Sheppard, Birger Brodin, Povl Krogsgaard-Larsen, Patrick O’Hara

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2001

Language:

english

File:

PDF, 837 KB

english, 2001

6

A Novel Route to 5-Substituted 3-Isoxazolols. Cyclization of N,O- DiBoc β-Keto Hydroxamic Acids Synthesized via Acyl Meldrum's Acids

Sørensen, Ulrik S., Falch, Erik, Krogsgaard-Larsen, Povl

Journal:

Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 68 KB

english, 2000

7

Glutamate receptors and new glutamate agonists

Povl Krogsgaard-Larsen, Tage Honore´

Journal:

Trends in Pharmacological Sciences

Year:

1983

Language:

english

File:

PDF, 316 KB

english, 1983

8

Ligands for Glutamate Receptors: Design and Therapeutic Prospects

Bräuner-Osborne, Hans, Egebjerg, Jan, Nielsen, Elsebet Ø., Madsen, Ulf, Krogsgaard-Larsen, Povl

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 1.48 MB

english, 2000

9

Clinical and psychometric validation of the psychotic depression assessment scale

Østergaard, Søren D., Pedersen, Christina H., Uggerby, Peter, Munk-Jørgensen, Povl, Rothschild, Anthony J., Larsen, Jens Ivar, Gøtzsche, Camilla, Søndergaard, Mia G., Bille, Anna Gry, Bolwig, Tom G.,

Journal:

Journal of Affective Disorders

Year:

2015

Language:

english

File:

PDF, 653 KB

english, 2015

10

Balanced scorecards and the FTSE 100: exploratory research

Tonge, Richard, Larsen, Povl, Pepper, Jonathan

Journal:

International Journal of Business Performance Management

Year:

2000

Language:

english

File:

PDF, 52 KB

english, 2000

11

Synthesis of tritiated (RS)-2-amino-2-(3-hydroxy-5-methylisoxazol-4-yl)acetic acid (AMAA), a potent and selective NMDA agonist

Tommy N. Johansen, Venkataraman Balasubramanian, Ulf Madsen, John W. Ferkany, Povl Krogsgaard-Larsen

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1996

Language:

english

File:

PDF, 329 KB

english, 1996

12

Synthesis of deuterium and tritium labelled (RS)-2-amino-3-(5-tert-butyl-3-hydroxy-4-isoxazolyl)-propionic acid (ATPA), a selective kainic acid receptor agonist

Tommy N. Johansen, Calvin R. Hawes, Gareth J. Ellis, Bjarke Ebert, Tine B. Stensbøl, Dorthe da Graça Thrige, Povl Krogsgaard-Larsen

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1999

File:

PDF, 315 KB

1999

13

AMPA receptor agonists: Resolution, configurational assignment, and pharmacology of (+)-(S)- and (-)-(R)-2-amino-3-[3-hydroxy-5-(2-pyridyl)-isoxazol-4-yl]-propionic acid (2-Py-AMPA)

Tommy N. Johansen, Bjarke Ebert, Erik Falch, Povl Krogsgaard-Larsen

Journal:

Year:

1997

Language:

english

File:

PDF, 173 KB

english, 1997

14

Excitatory amino acid receptor antagonists: Resolution, absolute stereochemistry, and pharmacology of (S)- and (R)-2-amino-2-(5-tert-butyl-3-hydroxyisoxazol-4-yl)acetic acid (ATAA)

Tommy N. Johansen, Karla Frydenvang, Bjarke Ebert, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Year:

1997

Language:

english

File:

PDF, 228 KB

english, 1997

15

Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1–4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

Eva H. Møller, Jan Egebjerg, Lotte Brehm, Tine B. Stensbøl, Tommy N. Johansen, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Year:

1999

Language:

english

File:

PDF, 702 KB

english, 1999

16

Solid phase synthesis and biological evaluation of enantiomerically pure wasp toxin analogues PhTX-343 and PhTX-12

Kristian Strømgaard, Inga Bjørnsdottir, Kim Andersen, Matthew J. Brierley, Silvio Rizoli, Nuri Eldursi, Ian R. Mellor, Peter N.R. Usherwood, Steen H. Hansen, Povl Krogsgaard-Larsen, Jerzy W. Jaroszews

Journal:

Year:

2000

Language:

english

File:

PDF, 204 KB

english, 2000

17

Resolution, configurational assignment, and enantiopharmacology of 2-amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5-yl)isoxazol-4-yl]propionic acid, a potent GluR3- and GluR4-preferring AMPA receptor agonist

Stine B. Vogensen, Henrik S. Jensen, Tine B. Stensbøl, Karla Frydenvang, Benny Bang-Andersen, Tommy N. Johansen, Jan Egebjerg, Povl Krogsgaard-Larsen

Journal:

Year:

2000

Language:

english

File:

PDF, 363 KB

english, 2000

18

Structural Determinants for AMPA Agonist Activity of Aryl or Heteroaryl Substituted AMPA Analogues. Synthesis and Pharmacology

Ulrik S. Sørensen, Erik Falch, Tine B. Stensbøl, Jerzy W. Jaroszewski, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Archiv der Pharmazie

Year:

2001

Language:

english

File:

PDF, 111 KB

english, 2001

19

Editorial: Die soziale Verantwortung der Wissenschaftler

Prof. Povl Krogsgaard-Larsen, Dr. Peter Thostrup, Prof. Flemming Besenbacher

Journal:

Angewandte Chemie

Year:

2011

Language:

german

File:

PDF, 351 KB

german, 2011

20

Editorial: Scientific Social Responsibility: A Call to Arms

Prof. Povl Krogsgaard-Larsen, Dr. Peter Thostrup, Prof. Flemming Besenbacher

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 345 KB

english, 2011

21

Analogues of Carbacholine: Synthesis and Relationship between Structure and Affinity for Muscarinic and Nicotinic Acetylcholine Receptors

Birgitte Søkilde, Ivan Mikkelsen, Tine B. Stensbøl, Birgit Andersen, Søren Ebdrup, Povl Krogsgaard-Larsen, Erik Falch

Journal:

Archiv der Pharmazie

Year:

1996

Language:

english

File:

PDF, 846 KB

english, 1996

22

ChemInform Abstract: Syntheses and GABA Receptor Binding Properties of 4-Amino-1-, 2-, and 3-hydroxybutylphosphinic Acids.

Jan Kehler, Bjarke Ebert, Otto Dahl, Povl Krogsgaard-Larsen

Journal:

Year:

1999

File:

PDF, 34 KB

1999

23

ChemInform Abstract: Piperidinyl-3-phosphinic Acids as Novel Uptake Inhibitors of the Neurotransmitter γ-Aminobutyric Acid (GABA).

Jan Kehler, Tine B. Stensboel, Povl Krogsgaard-Larsen

Journal:

Year:

1999

File:

PDF, 34 KB

1999

24

ChemInform Abstract: 3-Pyrazolone Analogues of the 3-Isoxazolol Metabotropic Excitatory Amino Acid Receptor Agonist Homo-AMPA. Synthesis and Pharmacological Testing.

Diane Zimmermann, Yves Louis Janin, Lotte Brehm, Hans Braeuner-Osborne, Bjarke Ebert, Tommy Noerskov Johansen, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Year:

2000

File:

PDF, 29 KB

2000

25

ChemInform Abstract: Selective Inhibitors of Glial GABA Uptake: Synthesis, Absolute Stereochemistry, and Pharmacology of the Enantiomers of 3-Hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and Analogues.

Povl Krogsgaard-Larsen, et al. et al.

Journal:

Year:

2000

Language:

english

File:

PDF, 36 KB

english, 2000

26

ChemInform Abstract: Synthesis and Pharmacology of Seleninic Acid Analogues of the Inhibitory Neurotransmitter γ-Aminobutyric Acid.

Nicolai Stuhr-Hansen, Bjarke Ebert, Povl Krogsgaard-Larsen, Jan Kehler

Journal:

Year:

2000

File:

PDF, 30 KB

2000

27

ChemInform Abstract: A Novel Route to 5-Substituted 3-Isoxazolols. Cyclization of N,O-DiBoc β-Keto Hydroxamic Acids Synthesized via Acyl Meldrum′s Acids.

Ulrik S. Soerensen, Erik Falch, Povl Krogsgaard-Larsen

Journal:

Year:

2000

File:

PDF, 36 KB

2000

28

ChemInform Abstract: Ionotropic Excitatory Amino Acid Receptor Ligands. Synthesis and Pharmacology of a New Amino Acid AMPA Antagonist.

Ulf Madsen, Frank A. Sloek, Tine B. Stensboel, Hans Braeuner-Osborne, Hans-Christian H. Luetzhoeft, Miguel V. Poulsen, Lisbeth Eriksen, Povl Krogsgaard-Larsen

Journal:

Year:

2000

File:

PDF, 29 KB

2000

29

ChemInform Abstract: Ligands for Glutamate Receptors: Design and Therapeutic Prospects

Hans Braeuner-Osborne, Jan Egebjerg, Elsebet Oe. Nielsen, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Year:

2000

File:

PDF, 25 KB

2000

30

ChemInform Abstract: Structural Determinants for AMPA Agonist Activity of Aryl or Heteroaryl Substituted AMPA Analogues. Synthesis and Pharmacology.

Ulrick S. Soerensen, Erik Falch, Tine B. Stensboel, Jerzy W. Jaroszewski, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Year:

2001

File:

PDF, 32 KB

2001

31

ChemInform Abstract: Synthesis and Pharmacology of 3-Isoxazolol Amino Acids as Selective Antagonists at Group I Metabotropic Glutamic Acid Receptors.

Ulf Madsen, Hans Braeuner-Osborne, Karla Frydenvang, Lise Hvene, Tommy N. Johansen, Birgitte Nielsen, Connie Sanchez, Tine B. Stensboel, Francois Bischoff, Povl Krogsgaard-Larsen

Journal:

Year:

2001

Language:

english

File:

PDF, 34 KB

english, 2001

32

ChemInform Abstract: A Convenient Synthesis of 4-Substituted 3-Ethoxy-5-methylisoxazoles by Palladium-Catalyzed Coupling Reactions.

Hasse Kromann, Frank A. Sloek, Tommy N. Johansen, Povl Krogsgaard-Larsen

Journal:

Year:

2001

File:

PDF, 32 KB

2001

33

ChemInform Abstract: Synthesis and Synthetic Utility of 3-Isoxazolols

Ulrik S. Soerensen, Povl Krogsgaard-Larsen

Journal:

Year:

2002

File:

PDF, 23 KB

2002

34

ChemInform Abstract: Mixed Cyano-Gilman Cuprates — Advances in Conjugate Addition to α,β-Unsaturated Pyroglutaminol.

Lennart Bunch, Povl Krogsgaard-Larsen, Ulf Madsen

Journal:

Year:

2002

File:

PDF, 29 KB

2002

35

ChemInform Abstract: Regioselective Lithiation and Functionalization of 3-(Benzyloxy)isothiazole: Application to the Synthesis of Thioibotenic Acid.

Lennart Bunch, Povl Krogsgaard-Larsen, Ulf Madsen

Journal:

Year:

2002

File:

PDF, 30 KB

2002

36

Design and Synthesis of a New Series of 4-Alkylated 3-Isoxazolol GABAA Antagonists.

Bente Froelund, Lena Tagmose, Anne T. Joergensen, Uffe Kristiansen, Tine B. Stensboel, Tommy Liljefors, Povl Krogsgaard-Larsen

Journal:

Year:

2003

File:

PDF, 64 KB

2003

37

Synthesis of Aryl- and Heteroaryl-Substituted 3-Benzyloxyisothiazoles via Suzuki and Negishi Cross-Coupling Reactions.

Birgitte H. Kaae, Povl Krogsgaard-Larsen, Tommy N. Johansen

Journal:

Year:

2004

File:

PDF, 116 KB

2004

38

Syntheses and GABA Uptake Properties of 6-Ether- and 6-Enol Ether-Substituted Nipecotic Acids.

Victor N'Goka, Caterina Bissantz, Philippe Bisel, Tine B. Stenboel, Povl Krogsgaard-Larsen, Gilbert Schlewer

Journal:

Year:

2004

File:

PDF, 23 KB

2004

39

Neuronal Nicotinic Acetylcholine Receptors: Structural Revelations, Target Identifications, and Therapeutic Inspirations

Anders A. Jensen, Bente Froelund, Tommy Liljefors, Povl Krogsgaard-Larsen

Journal:

Year:

2005

File:

PDF, 8 KB

2005

40

Glutamate receptor ligands: Synthesis, stereochemistry, and enantiopharmacology of methylated 2-aminoadipic acid analogs

Mette Guldbrandt, Tommy N. Johansen, Karla Frydenvang, Hans Bräuner-Osborne, Tine B. Stensbøl, Birgitte Nielsen, Rolf Karla, Flavio Santi, Povl Krogsgaard-Larsen, Ulf Madsen

Journal:

Year:

2002

Language:

english

File:

PDF, 225 KB

english, 2002

41

Stereostructure–activity studies on agonists at the AMPA and kainate subtypes of ionotropic glutamate receptors

Tommy N. Johansen, Jeremy R. Greenwood, Karla Frydenvang, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Year:

2003

Language:

english

File:

PDF, 408 KB

english, 2003

42

Resolution, configurational assignment, and enantiopharmacology at glutamate receptors of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) and demethyl-ACPA

Tommy N. Johansen, Tine B. Stensbøl, Birgitte Nielsen, Stine B. Vogensen, Karla Frydenvang, Frank A. Sløk, Hans Brünum, uner-Osborne, Ulf Madsen, Povl Krogsgaard-Larsen

Journal:

Year:

2001

Language:

english

File:

PDF, 511 KB

english, 2001

43

Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA

Lotte Brehm, Jeremy R. Greenwood, Frank A. Sløk, Mai Marie Holm, Birgitte Nielsen, Ulla Geneser, Tine B. Stensbøl, Hans Bräuner-Osborne, Mikael Begtrup, Jan Egebjerg, Povl Krogsgaard-Larsen

Journal:

Year:

2004

Language:

english

File:

PDF, 811 KB

english, 2004

44

GABAB antagonists: Resolution, absolute stereochemistry, and pharmacology of (R)- and (S)-phaclofen

Karla Frydenvang, Jan J. Hansen, Dr. Povl Krogsgaard-Larsen, Ann Mitrovic, Hue Tran, Colleen A. Drew, Graham A. R. Johnston

Journal:

Year:

1994

Language:

english

File:

PDF, 535 KB

english, 1994

45

GABAA agonists: Resolution and pharmacology of (+)- and (−)-isoguvacine oxide

Bente Frølund, Lone Jeppesen, Povl Krogsgaard-Larsen, Jan J. Hansen

Journal:

Year:

1995

Language:

english

File:

PDF, 523 KB

english, 1995

46

GABAB antagonists: Enantiopharmacology of 5-amino-4-hydroxy-2-methylvaleric acid and X-ray structure of the eutomer

Karla Frydenvang, Uffe Kristiansen, Bente Frølund, Claus Herdeis, Povl Krogsgaard-Larsen

Journal:

Year:

1995

Language:

english

File:

PDF, 694 KB

english, 1995

47

Medicinal chemistry education: what is needed and where is it going?

Povl Krogsgaard-Larsen, Roberto Pelliciari, Noel De Souza, Henk Timmerman, David J. Triggle, C. A. A. van Boeckel, Jan Wasley

Journal:

Drug Development Research

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

48

GABA-A agonists and GABA uptake inhibitors: Structure-activity relationships

Erik Falch, Orla M. Larsson, Arne Schousboe, Povl Krogsgaard-Larsen

Journal:

Drug Development Research

Year:

1990

Language:

english

File:

PDF, 1.24 MB

english, 1990

49

Preparations of deuterium labelled guvacine and isoguvacine

Søren Brøgger Christensen, Povl Krogsgaard-Larsen

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1980

Language:

english

File:

PDF, 443 KB

english, 1980

50

Deuterium labelling of the GABA agonists THIP, piperidine-4-sulphonic acid and the gaba uptake inhibitor THPO

Povl Krogsgaard-Larsen, Jørgen Stage Johansen, Erik Falch

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1982

Language:

english

File:

PDF, 470 KB

english, 1982